As the planner, you have made some changes to a few of the specifications for...

When the Demand and Supply Plan is run, verify that 'Recalculate Safety Stock' is selected in the Details section.

You are only able to update one item attribute at a time. Since you have changed multiple attributes, you will be unable to update and run this plan.

When the Demand and Supply Plan is run, verify that 'Refresh with current data' is selected in the Details section.

No additional steps are necessary. Any plans that contain your simulation set will automatically be updated with the changes.