A Campaign business practitioner creates populations in four queries: A, B, C, and D.

To meet the campaign requirements, the practitioner should first combine populations A and C using a Union activity, which will create a population that includes anyone from either group. Then, to identify those who should be excluded, populations B and D should be combined using an Intersect activity. This will identify recipients who are in both B and D. Finally, the Exclude activity should be used to remove anyone found in the intersection of B and D from the union of A and C. This results in a final targeting population that includes anyone from A or C but excludes anyone who is also in both B and D.References:The configuration is based on set theory and logical operations commonly used in database querying and manipulation, which are integral to creating targeting populations in campaign management systems like Adobe Campaign Classic.