Mid to distal septal akinesis in post-stress imaging of the apical four-chamber view is suggestive...

The mid to distal interventricular septum is supplied predominantly by the left anterior descending (LAD) coronary artery. Post-stress echocardiography showing akinesis or hypokinesis of these segments is highly suggestive of ischemia or infarction in the LAD territory.

The posterior descending artery supplies the inferior wall, the obtuse marginal supplies lateral walls, and the left circumflex supplies lateral and posterior walls.

This coronary artery segmental relationship is a cornerstone of ischemic heart disease evaluation by stress echocardiography and is well documented in ASE guidelines and clinical echocardiography literature【16:Textbook of Clinical Echocardiography, 6e†p.380-385】【12:ASE Stress Echocardiography Guidelines†p.300-310】.