The HITRUST CSF applies to covered information across all transmission and storage methods.

The HITRUST CSF is designed to apply comprehensively across alltransmission and storage methodsfor sensitive information. This includes:

Electronic transmission(e.g., email, secure messaging, EDI).

Physical storage and transfer(e.g., paper records, removable media).

Cloud storage and hosted environments.

Internal system storage(databases, file servers, applications).

By ensuring coverage across all methods, HITRUST aligns with regulatory expectations such as HIPAA, GDPR, and PCI-DSS, which emphasize protecting data inmotion, at rest, and in use. Organizations must implement technical, administrative, and physical controls to ensure that sensitive data is safeguarded regardless of its format or method of handling. This broad applicability makes the CSF a flexible framework capable of addressing modern hybrid IT and physical environments.