A client is given an opiate drug for pain relief following general anesthesia.

Tolerance is the capacity to ingest an increasing amount of a substance without effect and the experience of

decreased sensitivity to the substance. Tolerance can develop with long-term use of many drugs. Choice 1 is the

dose required to produce a defined magnitude of drug effect. Choice 3 binds to a receptor and causes an action.

Choice 4 is the maximal response produced by a drug.Pharmacological Therapies