A genomic research company analyzes approximately 50 TB of raw DNA sequence data for each...

The data isfrequently accessed only for the first 30 daysand then israrely accessedbut must be retained for7 years. That pattern matchesAmazon S3 Standardfor the initial active period and thenS3 Glacier Deep Archivefor long-term retention at the lowest storage cost. AWS guidance positions Glacier Deep Archive for long-lived archive data that is accessed once or twice a year and is ideal for compliance-style retention. EFS and EBS are not cost-effective archival storage choices for this use case. S3 Standard-IA is cheaper than S3 Standard, but Glacier Deep Archive is more cost-optimized for multi-year rare access.

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