A company’s infrastructure includes a Fibre Channel SAN where the VMware VMs are located.

For a VMware environment on a Fibre Channel SAN, the most efficient proxy transport mode to minimize impact on the production environment is Direct Storage Access. This mode allows the backup proxy to directly interact with the SAN, bypassing the production network and reducing load on the ESXi hosts.References: Veeam Backup & Replication Best Practices, Veeam VMware Backup Proxy Guide